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In an animal study, inhibition of the NF-B pathway led to a significant reduction in the expression of serum proinflammatory cytokines, including IL-6, IL-1 and TNF-, as well as an increase in the expression of the tight junction proteins occludin and ZO-1, thereby improving the function and structure of the intestinal mucosa

To emphasize that mature erythrocytes dont have the apoptotic mitochondrial machinery and distinguish this unique cell death modality from apoptosis, it was named eryptosis

doi: 10.1016/j.cmet.2009.08.001 75

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