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All the authors have read and approved the final manuscript

Stlhammar, 1990)

Melenovska, P

These circumstances lead to differences between DDA or MRM analyses (e.g., RLM (1D) compared to 3A4 (1D) in Table 3), leading to more found modified sites with RLM incubations than with Supersomes, even though the latter were less complex incubations