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TB500 is investigated for its association with actin polymerization dynamics and intracellular actin sequestration, which directly influences cell motility, differentiation, and structural reorganization

The SP-2509 lytic suppression effect was recapitulated with another target cell, the acute leukemia line, MOLM13, and furthermore was dose-dependent (Figure 4F)

Damiano VV, Tsang A, Kucich U, Abrams WR, Rosenbloom J, Kimbel P, Fallahnejad M, Weinbaum G: Immunolocalization of elastase in human emphysematous lungs