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Patient-centered studies (e.g., in acute COVID-19, i.e., with admission or within the first few weeks of the disease) frequently describe a severe dysbiosis, including decreased diversity and disappearance of beneficial taxa, at the acute end of infection [52]

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Using in vitro systems and animal based models, these studies have focused on characterizing receptor specificity, intracellular signaling fidelity, and the temporal organization of hormone secretion

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