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A large study involving 35 rhesus macaques, which were given prototype DNA vaccines expressing either full-length SARS-CoV-2 S protein or components of this protein, found that protection was correlated with the presence of neutralizing antibodiesand, notably, with Fc-dependent antibody effector functionsand there were no adverse outcomes after challenge 133

no KLOW trial Community approach Extended cycle Reported duration 8-12 weeks Reported break About 4 weeks Evidence level Reported in community protocols

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