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Glutathione-S-transferase P1 isoenzyme polymorphisms, platinum-based chemotherapy, and non-small cell lung cancer

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Relative gene expression was calculated by the 2 CT method using GAPDH as the internal reference gene ( TABLE 1 The primer pairs

Despite causing an increased susceptibility to OS, G6PD deficiency may also protect against CVD, since NADPH is an essential cofactor for enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA R), and G6PD deficiency or NADPH deficiency may restrain HMG-CoA R activity similarly to statins (Fig