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Mark Gordon Specializing in the treatment of symptomatic TBI, Gordon observed the significant role of hormonal imbalances in exacerbating neurological symptoms such as depression, anxiety, bipolar disorder, obsessive-compulsive disorder, dementia, Parkinson's disease, Gulf War Syndrome, and post-concussion syndrome

doi: 10.3389/fphar.2021.770663

In a previous study, mitochondrial fusion protein-2 (MFN2) enhanced mitochondria-endoplasmic reticulum (ER) contact and fostered inflow of mitochondrial Ca 2+ required for efficient mitochondrial metabolism by interacting with the ER-embedded Ca-ATPase SERCA2, thereby preventing mitochondrial Ca 2+ overaccumulation and apoptosis

For the most common forms of heavy metal intoxication lead, arsenic, or mercury a number of chelating agents are available