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rather, it participates systemically in the maintenance of lipid metabolic homeostasis through coordinated regulation across multiple signaling pathways and organ systems

Dermatitis is yet another common skin condition marked by inflammation and irritation on the skin

doi: 10.1042/bst20200672 131 XuZSunWLiYLingSZhaoCZhongGet al

These SASP components activate multiple signaling cascades, including the NF-B pathway, in neighboring cells, thereby propagating senescence and creating a pro-inflammatory microenvironment conducive to age-related pathologies[63]