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Second, independent of its role in GPX4 synthesis, selenomethionine exhibits intrinsic antioxidant properties by directly scavenging ROS through redox-active selenium moieties

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The evolution of intracellular parasitic lifestyle of Mtb could be in part due to the deletion of the cobF gene and the consequent need to uptake vitamin B12 from the host ( One of the major obstacles in controlling TB is the lack of a rapid but efficient diagnostic tool able to differentiate active TB from LTBI

Moreover, curcumin restores altered mitochondrial membranes, enabling ATP synthesis and providing a protective effect on mitochondria