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Notably, it has been identified that age at onset and extreme or typical phenotypes of PD are associated with polygenic rather than monogenic, and single-gene variants, including high-penetrance, mendelian alleles, are only discovered in 510% of all PD cases (Ye et al., 2023)

On the other hand, low sodium levels can cause fatigue, mood changes, and nausea

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also note if the article is in a language other than English." AAPCC "National Poisoning and Exposure Database Annual Reports (AAPCC Annual Data Reports)." American Association of Poison Control Centers 2008