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Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial

These results indicate that metformin increased GLUT1 membrane localization by decreasing TXNIP expression

Among all the individuals in the study, there was no significant difference in the development of acute liver failure in the setting of exposure to various NSAIDs with incidence of patients registered for liver transplantation in these cases being rare

The APC sent a formal letter to FDA Director Gail Bormel in October 2023, requesting transparency into the process used to make these decisions