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In a controlled study, patients (121 years of age) with newly diagnosed ALL or lymphoblastic lymphoma were given pegaspargase (2500 IU/M2, once induction, 15 doses every 2 weeks starting at week 7) or calaspargase pegol (2500 IU/M2, once induction, 10 doses every 3 weeks starting at week 7)

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the method comprises oral administration of a liposome suspension of reduced glutathione) where at least 30% of the reduced glutathione is entrapped in the aqueous spaces of the liposomes and therefore protected from degradation in the GI tract

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