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Description

& Mucinski, J

It is a quinolinium salt substituted at position 5 with an amino group and at position 1 with a methyl group

Combining NNMT inhibitors and traditional targeted drugs, including EGFR-TKIs and bevacizumab, can improve prognosis (63, 73)

Studies show that inhibiting nicotinamide Nmethyltransferase (NNMT) enhances metabolic health by reducing adipose tissue accumulation, improving insulin sensitivity, and promoting better energy utilization