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GHK-Cu (glycine-L-histidine-lysine) is a small copper-binding peptide, which has a remarkable and well-documented ability to improve wound healing and tissue regeneration, regulate remodeling of connective tissue and synthesis of collagen, elastin and glycosaminoglycans, reduce inflammation and scarring, increase antioxidant-enzymes and protect cells from toxic by-products of lipid peroxidation

In addition, a study showed that decitabine could enhance apoptosis induced by histone deacetyltransferase inhibitor (HDACi) depsipeptide in human thoracic cancer cells

Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors

Due to the complexity and heterogeneity of tumor metabolism, glutaminase blockade alone often leads to tumor cell resistance (Dos Reis et al., 2019)