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Modestly higher homocysteine, as predicted by genetics, was associated with an increased risk of stroke .[ref] High homocysteine levels can damage the endothelium (lining of the blood vessels) and cause hardening of the arteries.[ref] Related article : Heart disease genes Chronic diseases: Similarly, MR studies have shown that high homocysteine can cause metabolic syndrome , worsen osteoarthritis , increase the risk of cataracts, and increase the risk of Alzheimers disease

Although African Americans are less likely to develop skin cancer due to some natural sun protection provided by melanin in the skin, black patients who are diagnosed with skin cancer are, unfortunately, diagnosed in later stages than patients with light skin tones

Therefore, glutathione, itself, is not typically used in supplements

Cancer Immunol Res (2014) 2(9):82330