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Important: These findings are promising, but high-quality human trials remain limited

Inoue, W

Disrupting the alpha-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of parkinson's disease

While HRT can improve energy, libido, and bone health , it carries risks such as cancer, cardiovascular disease, and blood clots Rossouw et al., JAMA , 2002