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IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication

The Melbourne-based company, which does not manufacture the drug, claims it is a potential treatment for cartilage and muscle damage and even osteoarthritis, though there is absolutely no clinical evidence of that