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ArticlePubMedPMC 60

Patients may experience intense urges to gamble, increased sexual urges, intense urges to spend money, binge eating, and other intense urges, and the inability to control these urges while taking medications, including NEUPRO, that increase central dopaminergic tone

Examining in animals whether loss of enzymes such as IDH1/2 or GR is protective or sensitizing against pharmacological ER stresses on one hand, and overnutrition on the other, are needed to test this idea