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1 Thurston RC, El Khoudary SR, Sutton-Tyrrell K, et al

A single-centre study of 89 patients with relapsed or metastatic squamous cell HNC treated with Nivolumab showed that the median OS was significantly longer in patients with irAEs than those without (17.9 versus 6.3 months

Vial fell or was shaken accidentally If a reconstituted vial was shaken vigorously (dropped, thrown in a bag, held by a toddler), some peptide degradation may have occurred