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Future studies should examine this phenomenon in larger samples and focus on disentangling the relative contributions of each of these factors to the relationship between TL and antidepressant treatment resistance

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J Pharm Pharmacol 61:48791 Authement ME, Langlois LD, Kassis H, Gouty S, Dacher M, Shepard RD, Cox BM, Nugent FS (2016) Morphine-induced synaptic plasticity in the VTA is reversed by HDAC inhibition