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The high ROS environment lowers the activation threshold of mast cells, causing them to degranulate inappropriately and release a flood of inflammatory cytokines, including histamine, interleukins, and tumor necrosis factor-alpha (TNF-a)

Turpeinen, A

In a Several studies included in this review also found that acetyl-L-carnitine was as effective as antidepressant medications but caused fewer adverse effects

The researchers hypothesize that although there are dozens of genes that affect the metabolism of carnitine in the body, each gene might have a small effect, but no one gene has a severe disabling effect, such as often occurs in the more severe forms of autism