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10.7324/JABB.2023.110119 659

Diabetes is a major public health problem that is approaching epidemic proportions globally

However, melatonin treatment has reduced the production of collagen, hydroxyproline, laminin and hyaluronan in hepatic tissue, thus alleviating tetrachlormethaneinduced fibrosis (Hong et al., 2009) and tissue scarring in pinealectomised rats (Drobnik and Dabrowski, 1996)