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Under the influence of the extracellular matrix and inflammatory factors (FN1, FLNA, VCAN, CD44, FCN1, CXCL2, S100, CXCL3, etc.), e-MDSCs can transform into M-MDSCs

Neuroprotective observations included attenuation of traumatic brain injury-associated progression, spinal cord compression injury outcomes, and encephalopathy-associated changes in murine models

Therefore, concrete evidence, particularly in humans, is still lacking

Its unique amino acid sequence contributes to its classification as a stable gastric pentadecapeptide, allowing it to remain intact even in the challenging environment of human gastric juice