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In patients that met the NIT criteria, the following reasons were exclusionary from treatment with resmetirom based on the histological findings: 34 (9.3%) had cirrhosis on biopsy (F4), 117 (32.0%) had F0-F1, and 70 (19.1%) had F2-F3 but NAS 30% was defined as unreliable

4-Octyl itaconate alleviates dextran sulfate sodium-induced ulcerative colitis in mice via activating the KEAP1-NRF2 pathway

This imbalance is often observed in individuals facing stress conditions induced by free radicals or pathogenic infections

Since individual response to the medication varies, adjustments should be made under the guidance of a healthcare provider