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205,206 In addition, resident KCs attract circulating monocytes to sites of injury via CCL2 and indirectly stimulate endothelial cells to upregulate adhesion molecules like intercellular adhesion molecule 1 (ICAM-1), thereby enhancing monocyte recruitment

Discussion Psoriasis is characterized by chronic inflammation and the secretion of various cytokines from immune cells, leading to enhanced keratinocyte proliferation