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To minimise gastrointestinal side effects, the SmPC recommends gradual dose escalation

People who may experience symptoms of B12 excess usually fall into one of these categories: Taking very high-dose supplements regularly Receiving frequent B12 injections without medical supervision Having underlying health conditions affecting vitamin metabolism Experiencing allergic reactions to B12 formulations possible symptoms of too much B12

This article examines the main differences between methylcobalamin and cyanocobalamin two of the most common sources of vitamin B12 found in supplements

So, should you avoid biotin if you have acne