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The exclusion criteria were subjects with distant metastatic cancer, subjects undergoing immunotherapy, oral Tyrosine kinase inhibitors (TKI), or chemotherapy, participants who are being treated with additional experimental agents, uncontrolled concurrent illness that would make it more difficult to follow research guidelines, history of New York Heart Association Class III or IV heart failure, a myocardial infarction within the last six months, an uncontrolled cardiac arrhythmia, use of Luteinizing hormone-releasing hormone (LHRH) agonists, antagonists, Gonadotropin hormone-releasing hormone (GNRH) analogs, and antiandrogens in androgen deprivation therapy (ADT) or antiandrogen therapy and those subjects using Coumadin or Warfarin

Imanaka S, Shigetomi H, Kobayashi H (2022) Reprogramming of glucose metabolism of cumulus cells and oocytes and its therapeutic significance

To determine the total GSH content, 8505 C cells were stained with mBBr for 10 min in a 37 C incubator