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Moreover, as mitochondria play a central strategic role in the activation and mode of cell death, mitochondrial GSH has been shown to critically regulate the level of sensitization to secondary hits that induce mitochondrial membrane permeabilization and release of proteins confined in the intermembrane space that once in the cytosol engage the molecular machinery of cell death

Individual scores were summed to calculate the total Rapid Assessment of Modifiable Risk in Steatotic Liver Disease (RAMS) score (range 0-6)

Even at a high concentration of 320 g/mL, the hemolysis rate of PDA@Pt was only 3.2%, demonstrating the excellent safety profile of the nanodrug (Fig

K., Willerslev, E., Iversen, A