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Over expression of cytochrome P450-sensitized hepatocyte to TNF-mediated cell death was associated with increased LPO and GSH depletion [166]

Questi enzimi sono localizzati rispettivamente sulla superficie esterna della membrana mitocondriale esterna e sulla superficie interna della membrana mitocondriale interna e traslocano gruppi acilici da un lato all'altro della membrana