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The immune system identifies these translocated particles as dangerous invaders, launching an aggressive attack that results in systemic inflammation

Liquid chromatography (LC) coupled with mass-spectrometry (LC-MS) and gas chromatography (GC) coupled with MS (GC-MS) are two prominent metabolic profiling technologies covering a wide spectrum of cellular low-weight compounds ( 0.65, p-value 80%), while those for VAT and pancreatic islets performed adequately well (Supplementary Table S7) given the complexity of the data and the sample size

For instance, Benfluorex, which was approved in Europe in 1976 for lipid lowering and diabetes treatment, has been linked to PAH cases

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