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We previously reported that reduced levels of activated hepatocyte growth factor and the c-Met receptor tyrosine kinaseboth of which are vital for maintaining cellular redox balancecombined with increased expression of GJ proteins in hepsin-deficient mice

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Activation of ferroptosis and inhibition of myeloid suppressor cells (MDSC) combined with anti-PD-1 monoclonal antibody can greatly improve the survival rate of liver tumor mouse models and reduce liver metastasis of other tumors in situ (156)

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The finding, says Matt Savoca, a postdoctoral fellow at Stanford University in California and lead author of the study, suggests that helping whale populations rebound to preindustrial-whaling levels can have an even bigger effect on their ecosystems than previously thought

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