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Studies have found that Trx has a differential inhibitory effect on MMP-9, MMP-2, TIMP-1 and TIMP-2, thereby regulating the MMP/TIMP balance

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developed a model of Ox-LDL-induced ferroptosis in HUVECs, showing that CTRP13 intervention increased antioxidant enzyme expression, preventing AS and protecting endothelial cells from ferroptosis ( / mice by reducing mitochondrial damage, boosting glutathione and superoxide dismutase levels, and decreasing LPO and MDA levels