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Nitrite is a stable end product of NO metabolism, which converts hypochlorous acid into the more potent chlorinating species

The inflammatory signaling regulated by the NLRP3 inflammasome promotes abnormal SR Ca 2+ release and electrical remodeling in the atria of CM-specific knock-in mice expressing constitutively active NLRP3 [119]

2009) or MeHg-contaminated fish (Grotto et al

Concurrently, combined strategies that integrate metabolism-targeting agents with immunotherapy, chemotherapy, or radiotherapy must be designed to systematically overcome metabolic plasticity and treatment resistance in tumors, with the goal of systematically disrupt the metabolic adaptability of tumors