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Description

GS incorporates ammonia into glutamine by selectively expressing in hepatocytes, which becomes a fundamental source of nitrogen for amino acids and nucleotides 7,8

Oral bioavailability of 5-Amino-1MQ has not been characterised in any published pharmacokinetic study

Overall, UA demonstrates a broad capacity to reverse multidrug resistance in various cancer types, thereby enhancing the efficacy of common chemotherapy and targeted drugs