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Disclosures: Swati Ghosh: Nothing to Disclose, Michael Devereaux: Nothing to Disclose, Aimee Anderson: Nothing to Disclose, COLIN ANDERSON: BioMarin Pharmaceuticals: Employee, ANGELO D'ALESSANDRO: Nothing to Disclose, David Orlicky: Nothing to Disclose, Ronald Sokol: Nothing to Disclose 2474 MACROPHAGE-SPECIFIC HIF1 INHIBITION ACTIVATES HEPATIC STAT6 AND PROTECTS FROM PARENTERAL NUTRITION-ASSOCIATED CHOLESTASIS Swati Ghosh 1 Michael Devereaux 2 Karim el kasmi 2 Ronald Sokol 1 , 1 University of Colorado School of Medicine, 2 University of Colorado School ofMedicine Background: Chronic parenteral nutrition (PN) can lead to PN-associated cholestasis (PNAC)

Avoid Anti-Inflammatory Medications: NSAIDs (like ibuprofen) can interfere with PRPs healing response

Another factor contributing to their rating is the "Accountability Factor." If a batch is found to be out of spec by the community, Core Peptides has shown a documented history of pulling that entire lot from the shelves and issuing credits to affected researchers

Habib, R