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The reduced IGFBP binding affinity of LR3 extends its half-life, making it more practical for research protocols requiring sustained exposure

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Furthermore, given that the effects of 5-HT 2C agonists also include weight loss and a reduction in reward-seeking behaviors, the use of compounds that enhance 5-HT 2C signaling would also be clinically relevant for the treatment of obesity or to prevent relapse to drug abuse