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Promising OS and PFS data have been shown, especially in non-squamous taxane-nave NSCLC (n=42), with a median PFS of 6.4 months (95% CI, 4.5 to 10.5) and median OS of 16.3 months (95% CI, 11.5 to NR), compared to 3.5 months (95% CI, 2.7 to 5.3) and 11.2 months (95% CI, 8.3 to 13.7), respectively, in all NSCLC subtypes [87]

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Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha

The prevalence of drug-resistant epilepsy highlights a need to further understand underlying mechanisms in epilepsy such as neuroinflammation and consequential signaling cascades, as reviewed further elsewhere (Vezzani et al., 2019)