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Finally, B12 is required to make myelin, the protective layer that coats nerve cells. B12 also works alongside folate to produce red blood cells, and without adequate B12 those cells grow abnormally large and lose their ability to carry oxygen efficiently

The effects observed in chronic wounds likely reflect T4's ability to address multiple pathological features of impaired healing, including excessive inflammation, inadequate angiogenesis, impaired cell migration, and unfavorable extracellular matrix composition

To further confirm metabolic competence in selected liver cell models (PHH, HepG2 cells), CYP mRNA expression was investigated by quantitative polymerase chain reaction (qRT-PCR)

Despite these advantages, EDS may be less suitable for patients who are unable to generate reproducible exhalation manoeuvres and may entail greater device complexity and cost than conventional pump sprays