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This peptide works through multiple mechanisms: Modulates gene expression involved in tissue remodeling Increases collagen and elastin synthesis Promotes angiogenesis during tissue repair Shifts gene expression toward the TGF- pathway to reduce inflammation and restore connective tissue The copper component is critical because it activates lysyl oxidase enzymes that crosslink collagen and elastin fibers

In 1968, Bauer and Rathschlag-Schaefer reported that the oxygen half-saturation pressure, a measure of oxygen affinity, was higher in aldosterone-treated and cortisol-treated groups compared with the control group (Reference Bauer and Rathschlag-Schaefer55)

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All the sequences obtained were cross-checked for the presence of DJ-1/PfpI domain (PF01965.19)