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The long-term safety of repeated glutathione injections for skin lightening purposes is not fully established

Jiankun Xu, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

At the center of this sophisticated machinery lies a single, critical molecule: Glutathione (GSH)

In the contemporary era, research into these bioactive natural products originating from medicinal plants, fungi, and microorganisms is also based on ancient ethnopharmacological (including entheogenic) human practices [367, 590]