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This may be related to the large number of studies seeking approaches to combat antibiotic resistance (AMR), a major challenge to global public health that has resulted in hard-to-treat infections and a shortage of effective therapies [19,20]

Exploring whether inflammatory responses triggered by diverse sources can amplify the severity of ototoxicity [20] and collectively influence the MET channel's functionality is vital for a comprehensive understanding of these pathophysiological processes and for devising efficacious interventions

Jing Wu, Yan-Qiu You, et al

This is significant because age-related sleep disruption often involves not just melatonin deficiency but broader circadian gene dysfunction