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Immune-based approaches Immune-based therapeutic strategies have been suggested for some patients with BD and MDD, although due to the biological and clinical heterogeneity of these complex disorders, this type of therapy could be considered as a part of personalized approach, beneficiating approximately one in three patients, according to previous studies [333]

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As epitalon has been shown to bind to H1 (Khavinson et al 2020) it is possible that peptide may downregulate telomerase in cancer cells (through H1 binding and H19 upregulation), and activate ALT (through protein trapping) at the same time