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In contrast to PRX002, BIIB054 (Biogen) is a fully human-derived monoclonal antibody directed against the N-terminal epitope of -syn that exhibits a high level of specificity for aggregated and fibrillar forms of -syn with a more than 800-fold binding affinity for aggregated -syn compared with monomeric forms of the protein (Weihofen et al., 2019)

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Relationships of dietary habits with prostate cancer risk: results from Mendelian randomization analyses and the National Health and Nutrition Examination Survey