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Here we show morphine-induced constipation is mediated by a neural circuit from glutamatergic neurons in the paraventricular nucleus of hypothalamus (PVN Glu ) to acetylcholinergic neurons in the dorsal motor nucleus of the vagus (DMV Ach ), and subsequently to the small intestine in mice

The function of JMJD1A and JMJD1B to demethylate H3K9 is necessary to maintain the function of embryonic stem cells (ESC)

Sleep and circadian rhythm Sleep deprivation increases inflammatory cytokines and impairs Treg function

The balance between the need for NADPH or ribose 5-phosphate determines the direction of the non-oxidative arm (Wamelink et al., 2008)