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This system combined curcumin (Cur) and piperine (Pip) encapsulated within solid lipid nanoparticles (SLNs), along with tocopheryl polyethylene glycol succinate (TPGS) and Brij 78

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I3C and DIM regulate phase I biotransformation enzymes via AhR signaling The figure shows how indole-3-carbinol (I3C) and 3,3-diindolylmethane (DIM) regulate the expression of phase I biotransformation enzymes through the aryl hydrocarbon receptor (AhR) signaling pathway