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The presence of necrotic tissue together with apoptosis is consistent with defective efferocytosis in human plaques

Due to rapid growth and higher metabolic demands, children consume more food per kilogram of body weight than adults, making them especially vulnerable to contaminants such as aflatoxins, fumonisins, and ochratoxins commonly found in staple crops like maize and groundnuts [14,17]

This indicates that augmenting the function of missing beneficial microbes can tip the immune balance toward regulation rather than autoimmunity

The cause of PCOS is multifactorial, but the combination of genetic predisposition and eipgenetic impacts from environmental factors which switch on or off genes, make a woman with PCOS more prone to insulin resistance and chronic inflammation