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The toxic effects of nanomolar AFB 1 metabolites on oxidative status and immune cells (neutrophils, monocytes, lymphocytes, and dendritic cells [DCs]) in mammals are represented by increased free radicals, inflammatory molecules, and mitochondrial pathways of cell apoptosis (via caspase-3/7/9 activation and ATP depletion) (8688)

Tyrosol Ameliorates the Symptoms of Obesity, Promotes Adipose Thermogenesis, and Modulates the Composition of Gut Microbiota in HFD Fed Mice

QM/MM calculations Enzymesubstrate complexes were generated through molecular docking using the GOLD software 76 (ChemScore fitness function) on the crystal structure of PtGSTF8 preserving crystallographic Na + ions and flav-3-on-4-ol coordinates optimized at the B3LYP/6-31 G(d) quantum mechanical level (see below for details)