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Espinosa E, Murray T

Appl Eng Agric 17:9196

GHK-Cu operates upstream: it modulates the gene expression networks that regulate collagen synthesis, breakdown, and organization

The subsequent Phase 2b MONARCH combination study, which administered ARC-520 alongside entecavir and pegylated IFN-, faced enrollment challenges and reported early termination of several cohorts due to insufficient HbsAg clearance and safety issues [206]