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Recent evidence suggests that, even among hyperthyroid patients, maintaining an adequate dietary iodine intake improves therapeutic outcomes, enhancing response to treatment, reducing recurrence, increasing remission rates, and providing better control of thyrotoxicosis compared with inadequate or excessive iodine intake [40,41,42]

For Keap1, Nrf2, and Homx1 detection, Raw264.7 were cultured in six-well plates at a density of 3 10 5 cells/well

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Immunosuppressive cells also express arginase 1 (ARG1) and indoleamine 2,3-dioxygenase (IDO) which deplete levels of L-arginine and tryptophan, respectively, from the microenvironment and thus suppress the functions of effector immune cells [92] (Fig