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Its also needed for fatty acid metabolism and amino acid metabolism , which are key for energy and healthy tissues

Over production of either O 2 and H 2 O 2 has been associated with mitochondrial DNA, protein, and lipid damage, metabolic dysfunction and oxidative stress (Berlett and Stadtman, Mitochondria can be a major source of reactive oxygen species (ROS) in the aerobic cell (Brown and Borutaite, 2 consumed by mitochondria is converted to ROS (Chance et al., 2 saturation, and concentration of the redox active enzyme that can generate ROS

Mitochondrial dysfunction Mitochondria are indispensable organelles responsible for ATP production and coordination of calcium homeostasis, hormone synthesis, signal transduction, and apoptotic regulation 79,80